Testing on primates is currently an important tool for pharmaceutical development. The role of primates in creation and testing of new pharmaceutical products remains significant even in the light of the recent advances related to in vitro, in silico and other alternative laboratory testing models.
National BioService LLC in cooperation with Federal State Budgetary Scientific Institution «Research Institute of Medical Primatology» provide a wide range of research services involving non-human primates.
The Institute keeps about 5,500 animals (21 species with subspecies). The organization is fully accredited and licensed to breed and manage laboratory primates. The Institute’s activities comply with all international standards of scientific research and testing. All work is conducted exclusively within the 3RS concept (Refinement, Reduction, and Replacement). According to this concept, all specialists performing the tests are using and improving the techniques to reach the following targets:
- Reduce pain and stress impacts on animals.
- Reduce the number of participants to be tested.
- Animals in tests, whenever possible, are replaced by artificial objects.
Our research activities involve the following species of non-human primates
- Rhesus macaque (Macaca mulatta)
- Cynomolgous macaque (Macaca fascicularis)
- Hamadryas baboon (Papio hamadryas)
- Anubis baboon (Papio anubis)
- Green monkey (Chloro cebusaethiops).
- biological fluids (whole blood, serum, plasma, and other biological fluids upon request)
- tissues: fresh, frozen, embedded (in paraffin), tissue microarrays (TMAs)
- cells: PMBC, red blood cells, buffy coat layer, marrow cells, and other types of cells.
Our research services additionally include
- Studies assessing specificity and cross-reactivity of monoclonal antibodies using TMA based on normal tissue panels. The studies fully comply with the requirements of the US FDA law.
- Studies on TMA based on normal tissue panels of non-human primates according to customer requirements.
- Pharmacological and toxicological studies involving non-human primates.