Types of Biospecimens

National BioService possesses a rich collection of tissue samples and biofluids for research purposes. These types of biospecimens allow scientists to investigate ways of disease progression. Due to the biological samples, specialists develop brand new approaches for diagnostics and treatment and evaluate the efficiency of these methods. All collected specimens completely meet medical R&D needs.

National BioService provides the following biospecimens for research purposes in the following formats:

Tissue derivatives

  • Flash-frozen tissue (FF)
  • Formalin-fixed and paraffin embedded tissue (paraffin blocks, FFPE)
  • Unstained slides
  • Stained slides
  • Sections from FFPE blocks (curls)
  • Tissue frozen (embedded) in O.C.T. reagent
  • Tissue frozen in RNAlater reagent
  • Tissue lysates
  • Unstained and stained sections from O.C.T.-embedded tissues (Cryotome cuts) mounted over SuperFrost slides
  • Cryopreserved viable tissue fragments
  • Cryopreserved dissociated viable cells
  • Cryopreserved viable cells from primary cell cultures
  • Conditioned cultures, collected from in vitro cell cultures
  • Cryopreserved viable tumor-infiltrating lymphocytes (TIL)
  • Tissue microarrays (ТМА) of standard and customized design
  • Other

Derivatives of biofluids, including whole blood, bone marrow aspirate, urine, saliva, exudate, wound fluid, ascitic fluid, synovial fluid, etc.

  • Serum
  • Plasma (EDTA, Li-Hep, Na-Hep)
  • Double-spun plasma and triple-spun plasma (Citrate, Streck, etc.)
  • Flash-frozen saliva samples
  • Saliva samples with DNA stabilizer
  • Frozen urine samples
  • Isolated urine fractions (with cell pellet lysis, flash-freezing or cryopreservation, and supernatant freezing)
  • Frozen whole blood
  • Blood smears
  • Peripheral blood samples with DNA and RNA stabilizers
  • Cryopreserved viable peripheral blood mononuclear cells (PBMC)
  • Flash-frozen (FF) peripheral blood mononuclear cells (PBMC)
  • Dried blood spots
  • Flash-frozen bone marrow aspirate (BMA FF)
  • Bone marrow aspirate smears
  • Frozen coagulated bone marrow aspirate samples
  • Cryopreserved viable bone marrow mononuclear cells (BMMC)
  • Flash-frozen (FF) bone marrow mononuclear cells (BMMC)
  • FFPE blocks from bone marrow aspirate
  • Isolated fractions from various other biofluids (exudate, wound fluid, ascitic fluid, synovial fluid, etc.) (with cell pellet lysis, flash-freezing or cryopreservation, and supernatant freezing)
  • Cryopreserved viable cells and flash-frozen cells isolated by MACS technology (CD34+, CD133+, CD138+, etc.)
  • Other

Molecular biology

  • RNA from stabilized and flash-frozen tissue samples, with RIN measurement
  • RNA from stabilized blood samples, with RIN measurement
  • RNA from stabilized and flash-frozen bone marrow samples, with RIN measurement
  • DNA from various tissues
  • DNA from blood
  • DNA from bone marrow

 

 

17A Litovskaya str., Saint Petersburg